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Another way of synthesizing amino acids is the Gabriel (malonic-ester) synthesis, shown in Figure 10.8. Figure 10.8. Gabriel Synthesis An amino acid is generated from phthalimide and diethyl bromomalonate, using two S N 2 reactions, hydrolysis, and decarboxylation. In this method, potassium phthalimide is reacted with diethyl bromomalonate.

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